| Reaction Details |
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 | Report a problem with these data |
| Target | Microtubule-associated protein tau |
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| Ligand | BDBM50615175 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2299841 |
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| Ki | >1.5±n/a nM |
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| Citation |  Wongso, H; Ono, M; Yamasaki, T; Kumata, K; Higuchi, M; Zhang, MR; Fulham, MJ; Katsifis, A; Keller, PA Synthesis and structure-activity relationship (SAR) studies of 1,2,3-triazole, amide, and ester-based benzothiazole derivatives as potential molecular probes for tau protein. RSC Med Chem14:858-868 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Microtubule-associated protein tau |
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| Name: | Microtubule-associated protein tau |
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| Synonyms: | MAPT | MAPTL | MTBT1 | Microtubule-associated protein tau | Neurofibrillary tangle protein | PHF-tau | Paired helical filament-tau | TAU | TAU_HUMAN | Tau Protein |
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| Type: | Protein |
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| Mol. Mass.: | 78928.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10636 |
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| Residue: | 758 |
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| Sequence: | MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
DPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP
KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD
LSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEK
LDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDT
SPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
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| BDBM50615175 |
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| n/a |
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| Name | BDBM50615175 |
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| Synonyms: | CHEMBL5285051 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N5O3S |
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| Mol. Mass. | 367.382 |
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| SMILES | COc1ccc2nc(sc2c1)-c1cn(Cc2ccc(cc2)[N+]([O-])=O)nn1 |
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| Structure | 
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