| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-dependent protein kinase catalytic subunit gamma |
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| Ligand | BDBM50206006 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2302575 |
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| IC50 | 9330±n/a nM |
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| Citation |  Faisal, M; Saeed, A; Shahzad, D; Fattah, TA; Lal, B; Channar, PA; Mahar, J; Saeed, S; Mahesar, PA; Larik, FA Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives. Eur J Med Chem141:386-403 (2017) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-dependent protein kinase catalytic subunit gamma |
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| Name: | cAMP-dependent protein kinase catalytic subunit gamma |
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| Synonyms: | KAPCG_HUMAN | PKA C-gamma | PRKACG | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic subunit gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40442.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104720 |
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| Residue: | 351 |
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| Sequence: | MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
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| BDBM50206006 |
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| n/a |
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| Name | BDBM50206006 |
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| Synonyms: | 7,8-Dihydroxy-2H-1-benzopyran-2-one | 7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoumarin | CHEMBL244948 | Daphnetol |
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| Type | Small organic molecule |
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| Emp. Form. | C9H6O4 |
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| Mol. Mass. | 178.1415 |
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| SMILES | Oc1ccc2ccc(=O)oc2c1O |
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| Structure | 
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