| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50202110 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_423415 (CHEMBL909387) |
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| Ki | >10000±n/a nM |
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| Citation |  Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors. J Med Chem50:165-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | CCK-2 receptor | CCK-B receptor | CCK-BR | CCKBR | CCKRB | Cholecystokinin A | Cholecystokinin receptor | Cholecystokinin-2 Receptor | GASR_HUMAN | Gastrin/cholecystokinin type B receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48445.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Stable expression of human CCK-2 receptors in HEK 293 cells. |
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| Residue: | 447 |
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| Sequence: | MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
PDEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50202110 |
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| n/a |
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| Name | BDBM50202110 |
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| Synonyms: | CHEMBL218651 | H-Tyr-D-Ala-Gly-Phe-NH-NH-Trp-D-Nle-D-Asp-D-Phe-H |
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| Type | Small organic molecule |
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| Emp. Form. | C53H65N11O11 |
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| Mol. Mass. | 1032.1503 |
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| SMILES | CCCC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| |
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| Structure | 
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