| Reaction Details |
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 | Report a problem with these data |
| Target | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Ligand | BDBM50615881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2304680 |
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| IC50 | 1800±n/a nM |
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| Citation |  Okamoto, K; Ishikawa, A; Okawa, R; Yamamoto, K; Sato, T; Yokota, SI; Chiba, K; Ichikawa, S Design, synthesis and biological evaluation of simplified analogues of MraY inhibitory natural product with rigid scaffold. Bioorg Med Chem55:0 (2022) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Name: | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Synonyms: | MRAY_STAAU | mraY |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.55 |
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| Organism: | Staphylococcus aureus (strain MRSA252) |
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| Description: | ChEMBL_827497 |
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| Residue: | 321 |
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| Sequence: | MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIV
ITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAI
IFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATG
LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKV
VTVFWAVGLISGLIGLWIGVH
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| BDBM50615881 |
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| n/a |
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| Name | BDBM50615881 |
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| Synonyms: | CHEMBL5290020 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O9 |
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| Mol. Mass. | 490.4632 |
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| SMILES | [H][C@@]1(O[C@@H](C#Cc2cccc(N)c2)[C@@]2([H])O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H](CN)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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