| Reaction Details |
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 | Report a problem with these data |
| Target | KiSS-1 receptor |
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| Ligand | BDBM50203812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_425686 (CHEMBL912002) |
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| Ki | 3600±n/a nM |
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| Citation |  Orsini, MJ; Klein, MA; Beavers, MP; Connolly, PJ; Middleton, SA; Mayo, KH Metastin (KiSS-1) mimetics identified from peptide structure-activity relationship-derived pharmacophores and directed small molecule database screening. J Med Chem50:462-71 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| KiSS-1 receptor |
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| Name: | KiSS-1 receptor |
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| Synonyms: | AXOR12 | G-protein Coupled Receptor 54 | G-protein coupled receptor 54 (GPR54) | GPR54 | Hypogonadotropin-1 | KISS1R | KISSR_HUMAN | KiSS-1R | Kisspeptins receptor | Metastin receptor | hOT7T175 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42613.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Binding assay was performed using membranes from the CHO cell transfectants. |
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| Residue: | 398 |
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| Sequence: | MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGN
SLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLAL
HRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP
ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA
AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPH
AELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL
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| BDBM50203812 |
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| n/a |
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| Name | BDBM50203812 |
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| Synonyms: | CHEMBL221753 | benzethonium hydrochloride | cid_8478 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H42NO2 |
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| Mol. Mass. | 412.6273 |
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| SMILES | CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 |
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| Structure | 
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