| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 8 |
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| Ligand | BDBM50203893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_425774 (CHEMBL855766) |
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| IC50 | 19.6±n/a nM |
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| Citation |  Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem50:566-84 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 8 |
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| Name: | C-C chemokine receptor type 8 |
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| Synonyms: | CCR8 | CCR8_HUMAN | CKRL1 | CMKBR8 | CMKBRL2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40855.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_454278 |
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| Residue: | 355 |
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| Sequence: | MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
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| BDBM50203893 |
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| n/a |
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| Name | BDBM50203893 |
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| Synonyms: | 3-(2,6-dimethylmorpholin-4-yl)propyl-4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate | CHEMBL222020 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H42N4O6S |
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| Mol. Mass. | 622.775 |
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| SMILES | CC1CN(CCCOC(=O)N2CCC(CC2)NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC(C)O1 |
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| Structure | 
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