| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50204774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_454479 (CHEMBL886505) |
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| Ki | 2454±n/a nM |
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| Citation |  Caldwell, JP; Matasi, JJ; Zhang, H; Fawzi, A; Tulshian, DB Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands. Bioorg Med Chem Lett17:2281-4 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50204774 |
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| n/a |
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| Name | BDBM50204774 |
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| Synonyms: | 8-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL240870 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29N3O |
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| Mol. Mass. | 423.5494 |
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| SMILES | O=C1NCN(c2ccccc2)C11CCN(CC1)C1c2ccccc2CCc2ccccc12 |
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| Structure | 
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