| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50205834 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_428456 (CHEMBL918957) |
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| IC50 | 0.496±n/a nM |
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| Citation |  Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Dicarba analogues of the cyclic enkephalin peptides H-Tyr-c[D-Cys-Gly-Phe-D(or L)-Cys]NH(2) retain high opioid activity. J Med Chem50:1414-7 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40577.25 |
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| Organism: | MOUSE |
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| Description: | P32300 |
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| Residue: | 372 |
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| Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
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| BDBM50205834 |
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| n/a |
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| Name | BDBM50205834 |
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| Synonyms: | CHEMBL220333 | CHEMBL223244 | H-Tyr-c[D-Allylgly-Gly-Phe-L-Allylgly]NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34N6O6 |
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| Mol. Mass. | 550.6062 |
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| SMILES | N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O |w:15.15| |
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| Structure | 
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