| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2 |
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| Ligand | BDBM50055371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_428853 (CHEMBL917129) |
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| IC50 | 3300±n/a nM |
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| Citation |  Touaibia, M; Djimdé, A; Cao, F; Boilard, E; Bezzine, S; Lambeau, G; Redeuilh, C; Lamouri, A; Massicot, F; Chau, F; Dong, CZ; Heymans, F Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities. J Med Chem50:1618-26 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2 |
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| Name: | Phospholipase A2 |
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| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
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| Type: | Protein |
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| Mol. Mass.: | 16364.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04054 |
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| Residue: | 148 |
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| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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| BDBM50055371 |
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| n/a |
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| Name | BDBM50055371 |
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| Synonyms: | (3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-indol-4-yloxy)-acetic acid | CHEMBL357979 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N2O5 |
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| Mol. Mass. | 442.4633 |
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| SMILES | Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1-c1ccccc1 |
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| Structure | 
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