| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50207192 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_443023 (CHEMBL892154) |
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| IC50 | 553±n/a nM |
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| Citation |  Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore. Bioorg Med Chem15:3143-51 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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| BDBM50207192 |
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| n/a |
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| Name | BDBM50207192 |
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| Synonyms: | (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-5-amino-6-(benzylamino)-6-oxohexyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | CHEMBL396422 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H43N5O4 |
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| Mol. Mass. | 585.7363 |
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| SMILES | Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](N)C(=O)NCc1ccccc1 |
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| Structure | 
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