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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | B1 bradykinin receptor | ||
| Ligand | BDBM50210363 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_443978 (CHEMBL893140) | ||
| Ki | 3.7±n/a nM | ||
| Citation |  Su, DS; Lim, JL; Markowitz, MK; Wan, BL; Murphy, KL; Reiss, DR; Harrell, CM; O'Malley, SS; Ransom, RW; Chang, RS; Pettibone, DJ; Tang, C; Prueksaritanont, T; Freidinger, RM; Bock, MG Potent bradykinin B1 receptor antagonists: 4-substituted phenyl cyclohexanes. Bioorg Med Chem Lett17:3006-9 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| B1 bradykinin receptor | |||
| Name: | B1 bradykinin receptor | ||
| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 40508.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46663 | ||
| Residue: | 353 | ||
| Sequence: |
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| BDBM50210363 | |||
| n/a | |||
| Name | BDBM50210363 | ||
| Synonyms: | CHEMBL233886 | N-(2-((4-(2-chlorophenyl)-4-cyanocyclohexyl)methylamino)pyridin-3-yl)-3,3,3-trifluoropropanamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H22ClF3N4O | ||
| Mol. Mass. | 450.884 | ||
| SMILES | FC(F)(F)CC(=O)Nc1cccnc1NCC1CCC(CC1)(C#N)c1ccccc1Cl |(4.04,-13.65,;5.38,-14.42,;6.15,-13.09,;4.62,-15.75,;6.71,-15.19,;6.71,-16.73,;5.38,-17.49,;8.04,-17.51,;8.05,-19.05,;6.71,-19.81,;6.71,-21.36,;8.05,-22.13,;9.38,-21.36,;9.38,-19.81,;10.71,-19.03,;12.04,-18.25,;13.38,-19.01,;13.4,-20.56,;14.72,-21.33,;16.08,-20.52,;16.06,-18.98,;14.71,-18.23,;17.34,-19.63,;18.59,-18.74,;16.15,-22.05,;17.5,-22.77,;17.57,-24.31,;16.27,-25.12,;14.91,-24.41,;14.84,-22.87,;13.47,-22.16,)| | ||
| Structure | 
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