| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha |
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| Ligand | BDBM50214472 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_439083 (CHEMBL889431) |
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| Ki | 260±n/a nM |
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| Citation |  Nie, Z; Perretta, C; Erickson, P; Margosiak, S; Almassy, R; Lu, J; Averill, A; Yager, KM; Chu, S Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg Med Chem Lett17:4191-5 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha |
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| Name: | Casein kinase II subunit alpha |
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| Synonyms: | ACK2 | CK II | CK2- alpha | CSK2A_MAIZE | Casein Kinase II |
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| Type: | Enzyme |
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| Mol. Mass.: | 39238.74 |
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| Organism: | Zea mays (Maize) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKC
IIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLY
PTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPG
KEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKI
AKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLL
RYDHQERLTALEAMTHPYFQQVRAAENSRTRA
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| BDBM50214472 |
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| n/a |
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| Name | BDBM50214472 |
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| Synonyms: | CHEMBL231095 | N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE | N2,N4-diphenylpyrazolo[1,5-a][1,3,5]triazine-2,4-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N6 |
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| Mol. Mass. | 302.3333 |
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| SMILES | N(c1ccccc1)c1nc(Nc2ccccc2)n2nccc2n1 |
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| Structure | 
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