| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesteryl ester transfer protein |
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| Ligand | BDBM50101009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_448557 (CHEMBL897706) |
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| IC50 | 6790±n/a nM |
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| Citation |  Castilho, MS; Guido, RV; Andricopulo, AD 2D Quantitative structure-activity relationship studies on a series of cholesteryl ester transfer protein inhibitors. Bioorg Med Chem15:6242-52 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesteryl ester transfer protein |
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| Name: | Cholesteryl ester transfer protein |
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| Synonyms: | CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I |
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| Type: | Enzyme |
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| Mol. Mass.: | 54751.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11597 |
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| Residue: | 493 |
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| Sequence: | MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
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| BDBM50101009 |
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| n/a |
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| Name | BDBM50101009 |
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| Synonyms: | 1,1,1-Trifluoro-3-[[3-(1-methyl-1H-pyrrol-2-yl)-benzyl]-(3-phenoxy-phenyl)-amino]-propan-2-ol | 1,1,1-trifluoro-3-((3-(1-methyl-1H-pyrrol-2-yl)benzyl)(3-phenoxyphenyl)amino)propan-2-ol | 3-((3-(1-methyl-1H-pyrrol-2-yl)benzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol | CHEMBL43764 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25F3N2O2 |
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| Mol. Mass. | 466.4948 |
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| SMILES | Cn1cccc1-c1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1 |
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| Structure | 
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