| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
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| Ligand | BDBM50220547 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_457331 (CHEMBL941864) |
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| Ki | 800±n/a nM |
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| Citation |  Tasdemir, D; Topaloglu, B; Perozzo, R; Brun, R; O'Neill, R; Carballeira, NM; Zhang, X; Tonge, PJ; Linden, A; Rüedi, P Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. Bioorg Med Chem15:6834-45 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl-carrier protein reductase |
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| Name: | Enoyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49770.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_795989 |
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| Residue: | 432 |
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| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
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| BDBM50220547 |
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| n/a |
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| Name | BDBM50220547 |
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| Synonyms: | 4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-amino-1H-imidazol-4-yl)-allyl]-amide | 4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-amino-3H-imidazol-4-yl)-allyl]-amide | CHEMBL397591 | oroidin | oroidin base |
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| Type | Small organic molecule |
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| Emp. Form. | C11H11Br2N5O |
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| Mol. Mass. | 389.046 |
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| SMILES | Nc1ncc(C=CCNC(=O)c2cc(Br)c(Br)[nH]2)[nH]1 |w:6.6| |
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| Structure | 
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