| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM50221364 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_449579 (CHEMBL897620) |
|---|
| Ki | 500±n/a nM |
|---|
| Citation |  Sasse, BC; Mach, UR; Leppaenen, J; Calmels, T; Stark, H Hybrid approach for the design of highly affine and selective dopamine D(3) receptor ligands using privileged scaffolds of biogenic amine GPCR ligands. Bioorg Med Chem15:7258-73 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 44243.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 400 |
|---|
| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
|
|
|
|---|
| BDBM50221364 |
|---|
| n/a |
|---|
| Name | BDBM50221364 |
|---|
| Synonyms: | CHEMBL239066 | N-[4-(2,3,4,5,10,15-hexahydro-1H-dibenzo[b:e]-pyrazino[2,1-g]azepin-1-yl)butyl]thiophen-2-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H29N3OS |
|---|
| Mol. Mass. | 431.593 |
|---|
| SMILES | O=C(NCCCCN1CCN2C(C1)c1ccccc1Cc1ccccc21)c1cccs1 |w:11.11| |
|---|
| Structure | 
|
|---|
Search and Browse
