| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50221377 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_449579 (CHEMBL897620) |
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| Ki | 30.2±n/a nM |
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| Citation |  Sasse, BC; Mach, UR; Leppaenen, J; Calmels, T; Stark, H Hybrid approach for the design of highly affine and selective dopamine D(3) receptor ligands using privileged scaffolds of biogenic amine GPCR ligands. Bioorg Med Chem15:7258-73 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50221377 |
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| n/a |
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| Name | BDBM50221377 |
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| Synonyms: | CHEMBL429462 | N-[4-(4-diphenylmethylpiperazin-1-yl)butyl]cyclohexancarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H39N3O |
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| Mol. Mass. | 433.6288 |
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| SMILES | O=C(NCCCCN1CCN(CC1)C(c1ccccc1)c1ccccc1)C1CCCCC1 |
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| Structure | 
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