| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase A1 |
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| Ligand | BDBM50411600 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_462453 (CHEMBL928318) |
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| Ki | 4600±n/a nM |
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| Citation |  Deaton, DN; Graham, KP; Gross, JW; Miller, AB Thiol-based angiotensin-converting enzyme 2 inhibitors: P1' modifications for the exploration of the S1' subsite. Bioorg Med Chem Lett18:1681-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase A1 |
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| Name: | Carboxypeptidase A1 |
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| Synonyms: | CBPA1_HUMAN | CPA | CPA1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47132.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496378 |
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| Residue: | 419 |
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| Sequence: | MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG
SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA
TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS
REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR
SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK
AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA
SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
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| BDBM50411600 |
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| n/a |
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| Name | BDBM50411600 |
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| Synonyms: | CHEMBL251809 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26F3NO4S |
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| Mol. Mass. | 469.517 |
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| SMILES | CC[C@@H](C)[C@H](S)C(=O)N[C@@H](Cc1ccc(OCc2ccc(cc2)C(F)(F)F)cc1)C(O)=O |
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| Structure | 
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