Ki Summary

Reaction Details

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Target

Acetylcholinesterase

Ligand

BDBM50242346

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_509217 (CHEMBL995129)

IC50

50100±n/a nM

Citation

Kalauni, SK; Choudhary, MI; Shaheen, F; Manandhar, MD; Atta-ur-Rahman, A; Gewali, MB; Khalid, A Steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin. J Nat Prod64:842-4 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

Acetylcholinesterase

Name:

Acetylcholinesterase

Synonyms:

ACES_ELEEL | Acetylcholinesterase (AChE) | Acetylcholinesterase (EeAChE) | ache

Type:

Enzyme

Mol. Mass.:

71812.79

Organism:

Electrophorus electricus (Electric eel)

Description:

n/a

Residue:

633

Sequence:

MKILDALLFPVIFIMFFIHLSIAQTDPELTIMTRLGQVQGTRLPVPDRSHVIAFLGIPFA
EPPLGKMRFKPPEPKKPWNDVFDARDYPSACYQYVDTSYPGFSGTEMWNPNRMMSEDCLY
LNVWVPATPRPHNLTVMVWIYGGGFYSGSSSLDVYDGRYLAHSEKVVVVSMNYRVSAFGF
LALNGSAEAPGNVGLLDQRLALQWVQDNIHFFGGNPKQVTIFGESAGAASVGMHLLSPDS
RPKFTRAILQSGVPNGPWRTVSFDEARRRAIKLGRLVGCPDGNDTDLIDCLRSKQPQDLI
DQEWLVLPFSGLFRFSFVPVIDGVVFPDTPEAMLNSGNFKDTQILLGVNQNEGSYFLIYG
APGFSKDNESLITREDFLQGVKMSVPHANEIGLEAVILQYTDWMDEDNPIKNREAMDDIV
GDHNVVCPLQHFAKMYAQYSILQGQTGTASQGNLGWGNSGSASNSGNSQVSVYLYMFDHR
ASNLVWPEWMGVIHGYEIEFVFGLPLEKRLNYTLEEEKLSRRMMKYWANFARTGNPNINV
DGSIDSRRRWPVFTSTEQKHVGLNTDSLKVHKGLKSQFCALWNRFLPRLLNVTENIDDAE
RQWKAEFHRWSSYMMHWKNQFDHYSKQERCTNL

BDBM50242346

n/a

Name

BDBM50242346

Synonyms:

CHEMBL500603 | [(20S)-20-(N-methylamino)-3beta-(tigloylamino)-5alpha-pregn-16-en-2 beta,4 beta-diacetate]

Type

Small organic molecule

Emp. Form.

C31H48N2O5

Mol. Mass.

528.7232

SMILES

CN[C@@H](C)C1=CC[C@H]2[C@@H]3CC[C@H]4[C@@H](OC(C)=O)[C@@H](NC(=O)C(\C)=C\C)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)OC(C)=O |r,t:4|

Structure