| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyribonuclease-2-alpha |
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| Ligand | BDBM50242374 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509270 (CHEMBL996014) |
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| IC50 | >250000±n/a nM |
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| Citation |  Suzuki, K; Yahara, S; Maehata, K; Uyeda, M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod64:204-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyribonuclease-2-alpha |
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| Name: | Deoxyribonuclease-2-alpha |
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| Synonyms: | DNASE2 | DNASE2A | DNL2 | DNS2A_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40189.42 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_509270 |
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| Residue: | 364 |
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| Sequence: | MATLSPLLLAALLWVPVGTLTCYGDSGQPVDWFVVYKLPAHSSPGDVAQSGLRYKYLDEE
SGGWRDGAGSINSSTGALGRSLLPLYRNTSQLAFLLYNDQPPKYRGSQHSSNRGHTKGVL
LLDQEGGFWLIHSVPNFPPPSSSAAYSWPPSARTYGQTLICVSFPLTQFLNISRQLTYTY
PMVYDYKLEGDFARKFPYLEEVVKGHHVLQEPWNSSVTLTSKAGASFQSFAKCGNFGDDL
YSGWLAEALGSNLQVQFWQRSAGILPSNCSGVQHVLDVTQIAFPGPAGPNFNATEDHSKW
CVAPERPWTCVGDMNRNKREEHRGGGTLCAQLPALWKAFKPLVKAWEPCEKENRAFSPRS
PAKD
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| BDBM50242374 |
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| n/a |
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| Name | BDBM50242374 |
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| Synonyms: | CHEMBL505529 | topostatin |
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| Type | Small organic molecule |
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| Emp. Form. | C36H58N4O11S |
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| Mol. Mass. | 754.931 |
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| SMILES | CCCCCCCC(C)CC=C(C)C=CC(=O)C(C)CCC1OC(=O)[C@H](CC(OS(O)(=O)=O)C(N)=O)NC(=O)[C@@H](C)CNC(=O)C(=C)NC(=O)C1C |r,w:14.14,10.9| |
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| Structure | 
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