| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50251193 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_531309 (CHEMBL989721) |
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| IC50 | 2620±n/a nM |
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| Citation |  Moloney, GP; Angus, JA; Robertson, AD; Stoermer, MJ; Robinson, M; Wright, CE; McRae, K; Christopoulos, A Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor. Eur J Med Chem43:513-39 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50251193 |
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| n/a |
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| Name | BDBM50251193 |
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| Synonyms: | 3-[3-Benzyl-[1,2,4]oxadiazol-5-yl]-1-(2-morpholin-4-yl-ethyl)-1H-indole | CHEMBL517157 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N4O2 |
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| Mol. Mass. | 388.4623 |
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| SMILES | C(Cn1cc(-c2nc(Cc3ccccc3)no2)c2ccccc12)N1CCOCC1 |
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| Structure | 
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