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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Squalene synthase | ||
| Ligand | BDBM50270321 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_520604 (CHEMBL959526) | ||
| IC50 | 250±n/a nM | ||
| Citation |  Cammerer, SB; Jimenez, C; Jones, S; Gros, L; Lorente, SO; Rodrigues, C; Rodrigues, JC; Caldera, A; Ruiz Perez, LM; da Souza, W; Kaiser, M; Brun, R; Urbina, JA; Gonzalez Pacanowska, D; Gilbert, IH Quinuclidine derivatives as potential antiparasitics. Antimicrob Agents Chemother51:4049-61 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Squalene synthase | |||
| Name: | Squalene synthase | ||
| Synonyms: | FDFT1 | FDFT_HUMAN | FPP:FPP farnesyltransferase | Farnesyl-diphosphate farnesyltransferase | SQS | SS | Squalene synthetase | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 48114.76 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1352847 | ||
| Residue: | 417 | ||
| Sequence: |
| ||
| BDBM50270321 | |||
| n/a | |||
| Name | BDBM50270321 | ||
| Synonyms: | 3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene | CHEMBL453439 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H21NO | ||
| Mol. Mass. | 291.3868 | ||
| SMILES | C(Oc1ccc(cc1)C1=CN2CCC1CC2)c1ccccc1 |t:9,(-1.9,-8.72,;-3.23,-7.95,;-4.56,-8.72,;-4.56,-10.26,;-5.9,-11.03,;-7.23,-10.25,;-7.23,-8.72,;-5.9,-7.95,;-8.56,-11.02,;-8.56,-12.57,;-9.9,-13.34,;-11.24,-12.57,;-11.24,-11.02,;-9.9,-10.24,;-10.64,-11.6,;-9.15,-12.01,;-.56,-7.95,;.76,-8.72,;2.1,-7.95,;2.1,-6.41,;.75,-5.64,;-.57,-6.42,)| | ||
| Structure | 
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