Reaction Details | |||
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Target | Squalene synthase | ||
Ligand | BDBM50270323 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_520603 (CHEMBL959525) | ||
IC50 | >1000±n/a nM | ||
Citation | Cammerer, SB; Jimenez, C; Jones, S; Gros, L; Lorente, SO; Rodrigues, C; Rodrigues, JC; Caldera, A; Ruiz Perez, LM; da Souza, W; Kaiser, M; Brun, R; Urbina, JA; Gonzalez Pacanowska, D; Gilbert, IH Quinuclidine derivatives as potential antiparasitics. Antimicrob Agents Chemother51:4049-61 (2007) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Squalene synthase | |||
Name: | Squalene synthase | ||
Synonyms: | Farnesyltransferase, putative | ||
Type: | PROTEIN | ||
Mol. Mass.: | 47117.40 | ||
Organism: | Leishmania major | ||
Description: | ChEMBL_520603 | ||
Residue: | 414 | ||
Sequence: |
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BDBM50270323 | |||
n/a | |||
Name | BDBM50270323 | ||
Synonyms: | 3-(3'-Quinolyl)-quinuclidine-2-ene | CHEMBL478340 | ||
Type | Small organic molecule | ||
Emp. Form. | C16H16N2 | ||
Mol. Mass. | 236.3116 | ||
SMILES | C1CN2CCC1C(=C2)c1cnc2ccccc2c1 |c:7,(20.51,-11.4,;20.51,-12.95,;21.84,-13.72,;22.59,-12.38,;21.11,-11.98,;21.84,-10.63,;23.18,-11.4,;23.18,-12.95,;24.51,-10.64,;25.84,-11.41,;27.17,-10.64,;27.17,-9.1,;28.5,-8.33,;28.5,-6.79,;27.15,-6.02,;25.83,-6.8,;25.83,-8.33,;24.51,-9.1,)| | ||
Structure |