| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-9 |
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| Ligand | BDBM50270346 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_530307 (CHEMBL980369) |
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| IC50 | 93000±n/a nM |
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| Citation |  Sakai, J; Yoshimori, A; Nose, Y; Mizoroki, A; Okita, N; Takasawa, R; Tanuma, S Structure-based discovery of a novel non-peptidic small molecular inhibitor of caspase-3. Bioorg Med Chem16:4854-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-9 |
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| Name: | Caspase-9 |
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| Synonyms: | Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 | ICE-like apoptotic protease 6 | MCH6 | caspase-9 isoform alpha preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 46277.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 416 |
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| Sequence: | MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
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| BDBM50270346 |
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| n/a |
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| Name | BDBM50270346 |
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| Synonyms: | 4-(ethoxycarbonylmethoxy)-1-hydroxy-naphthalene-2-carboxylic acid | CHEMBL479009 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14O6 |
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| Mol. Mass. | 290.2681 |
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| SMILES | CCOC(=O)COc1cc(C(O)=O)c(O)c2ccccc12 |
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| Structure | 
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