| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione hydrolase 1 proenzyme |
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| Ligand | BDBM22360 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543160 (CHEMBL1014320) |
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| IC50 | 36000±n/a nM |
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| Citation |  Sadanandam, YS; Shetty, MM; Rao, AB; Rambabu, Y 10H-Phenothiazines: a new class of enzyme inhibitors for inflammatory diseases. Eur J Med Chem44:197-202 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione hydrolase 1 proenzyme |
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| Name: | Glutathione hydrolase 1 proenzyme |
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| Synonyms: | GGT | GGT1 | GGT1_HUMAN | Gamma-glutamyltranspeptidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61413.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_543160 |
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| Residue: | 569 |
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| Sequence: | MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRD
GGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFN
SSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALEN
KRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKD
IQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSR
ESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISD
DTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNE
MDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTA
TALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTF
IAVVQAIVRTAGGWAAASDSRKGGEPAGY
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| BDBM22360 |
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| n/a |
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| Name | BDBM22360 |
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| Synonyms: | 2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid | Acetylsalicylic acid | Aspirin | Endosprin | Polopirin | Zorprin | acetylsalicylate | cid_2244 |
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| Type | Anti-Inflammatory Agents, Non-Steroidal |
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| Emp. Form. | C9H8O4 |
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| Mol. Mass. | 180.1574 |
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| SMILES | CC(=O)Oc1ccccc1C(O)=O |
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| Structure | 
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