| Reaction Details |
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 | Report a problem with these data |
| Target | Queuine tRNA-ribosyltransferase catalytic subunit 1 |
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| Ligand | BDBM50271082 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_553551 (CHEMBL958734) |
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| Ki | 3700±n/a nM |
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| Citation |  Congreve, M; Chessari, G; Tisi, D; Woodhead, AJ Recent developments in fragment-based drug discovery. J Med Chem51:3661-80 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Queuine tRNA-ribosyltransferase catalytic subunit 1 |
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| Name: | Queuine tRNA-ribosyltransferase catalytic subunit 1 |
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| Synonyms: | QTRT1 | Queuine tRNA-ribosyltransferase | TGT | TGT_HUMAN | TGUT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44051.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_553551 |
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| Residue: | 403 |
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| Sequence: | MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTE
QLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEV
TEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIR
WLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFW
RMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQ
LRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAV
RTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG
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| BDBM50271082 |
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| n/a |
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| Name | BDBM50271082 |
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| Synonyms: | 4-(4-methoxyphenethyl)-6-amino-3H-imidazo[4,5-g]quinazolin-8(7H)-one | 6-AMINO-4-[2-(4-METHOXYPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE | CHEMBL487739 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N5O2 |
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| Mol. Mass. | 335.3599 |
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| SMILES | COc1ccc(CCc2c3[nH]cnc3cc3c2nc(N)[nH]c3=O)cc1 |
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| Structure | 
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