| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
|---|
| Ligand | BDBM50135883 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_553536 (CHEMBL958719) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Congreve, M; Chessari, G; Tisi, D; Woodhead, AJ Recent developments in fragment-based drug discovery. J Med Chem51:3661-80 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urokinase-type plasminogen activator |
|---|
| Name: | Urokinase-type plasminogen activator |
|---|
| Synonyms: | 3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48528.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00749 |
|---|
| Residue: | 431 |
|---|
| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
|
|
|
|---|
| BDBM50135883 |
|---|
| n/a |
|---|
| Name | BDBM50135883 |
|---|
| Synonyms: | (2R)-1-(2,6-dimethylphenoxy)propan-2-amine | (R)-1-(2,6-dimethylphenoxy)propan-2-amine | (R)-2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine | CHEMBL147507 | MEXILETINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H17NO |
|---|
| Mol. Mass. | 179.2588 |
|---|
| SMILES | C[C@@H](N)COc1c(C)cccc1C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
