| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl2-associated agonist of cell death |
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| Ligand | BDBM50270876 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_553538 (CHEMBL958721) |
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| IC50 | 6900±n/a nM |
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| Citation |  Congreve, M; Chessari, G; Tisi, D; Woodhead, AJ Recent developments in fragment-based drug discovery. J Med Chem51:3661-80 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bcl2-associated agonist of cell death |
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| Name: | Bcl2-associated agonist of cell death |
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| Synonyms: | BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18393.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_478760 |
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| Residue: | 168 |
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| Sequence: | MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSH
HGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDE
FVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
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| BDBM50270876 |
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| n/a |
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| Name | BDBM50270876 |
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| Synonyms: | 3-((E)-2-Biphenyl-3-yl-vinyl)-4'-fluoro-biphenyl-4-carboxylic acid | CHEMBL485891 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H19FO2 |
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| Mol. Mass. | 394.437 |
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| SMILES | OC(=O)c1ccc(cc1\C=C\c1cccc(c1)-c1ccccc1)-c1ccc(F)cc1 |
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| Structure | 
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