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TargetPeroxisome proliferator-activated receptor gamma
LigandBDBM50271605
Substrate/Competitorn/a
Meas. Tech.ChEMBL_556513 (CHEMBL956508)
IC50 200±n/a nM
Citation Sundriyal, SViswanad, BBharathy, ERamarao, PChakraborti, AKBharatam, PV New PPARgamma ligands based on 2-hydroxy-1,4-naphthoquinone: computer-aided design, synthesis, and receptor-binding studies. Bioorg Med Chem Lett18:3192-5 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peroxisome proliferator-activated receptor gamma
Name:Peroxisome proliferator-activated receptor gamma
Synonyms:Nr1c3 | PPARG_RAT | Pparg
Type:PROTEIN
Mol. Mass.:57562.54
Organism:Rattus norvegicus
Description:ChEMBL_642067
Residue:505
Sequence:
MGETLGDPPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMDDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
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  Blast E-value cutoff:
BDBM50271605
n/a
NameBDBM50271605
Synonyms:2-(4-(2-fluorobenzyloxy)benzyl)-3-hydroxynaphthalene-1,4-dione | CHEMBL482525
TypeSmall organic molecule
Emp. Form.C24H17FO4
Mol. Mass.388.3878
SMILESFc1ccccc1COc1ccc(CC2C(=O)C(=O)c3ccccc3C2=O)cc1
Structure
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