| Reaction Details |
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 | Report a problem with these data |
| Target | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Ligand | BDBM50262593 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_489248 (CHEMBL989995) |
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| Kd | 200000±n/a nM |
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| Citation |  Prakesch, M; Denisov, AY; Naim, M; Gehring, K; Arya, P The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1. Bioorg Med Chem16:7443-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Synonyms: | Bcl-2-related protein EAT/mcl1 | MCL1_MOUSE | Mcl-1 | Mcl1 |
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| Type: | Developmental protein |
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| Mol. Mass.: | 35215.08 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 331 |
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| Sequence: | MFGLRRNAVIGLNLYCGGASLGAGGGSPAGARLVAEEAKARREGGGEAALLPGARVVARP
PPVGAEDPDVTASAERRLHKSPGLLAVPPEEMAASAAAAIVSPEEELDGCEPEAIGKRPA
VLPLLERVSEAAKSSGADGSLPSTPPPPEEEEDDLYRQSLEIISRYLREQATGSKDSKPL
GEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVT
NWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFF
HVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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| BDBM50262593 |
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| n/a |
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| Name | BDBM50262593 |
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| Synonyms: | 2-((2S,3R,4S)-4-(2-naphthamido)-3-hydroxy-6-((2-methoxyethoxy)methoxy)-1-((2-(trimethylsilyl)ethoxy)carbonyl)-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid | CHEMBL446996 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N2O9Si |
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| Mol. Mass. | 624.7535 |
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| SMILES | COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)OCC[Si](C)(C)C |r| |
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| Structure | 
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