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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Peroxisome proliferator-activated receptor alpha | ||
| Ligand | BDBM50261702 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_513557 (CHEMBL979053) | ||
| EC50 | 0.272±n/a nM | ||
| Citation |  Pingali, H; Jain, M; Shah, S; Makadia, P; Zaware, P; Goel, A; Patel, M; Giri, S; Patel, H; Patel, P Design and synthesis of novel oxazole containing 1,3-dioxane-2-carboxylic acid derivatives as PPAR alpha/gamma dual agonists. Bioorg Med Chem16:7117-27 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Peroxisome proliferator-activated receptor alpha | |||
| Name: | Peroxisome proliferator-activated receptor alpha | ||
| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 52222.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07869 | ||
| Residue: | 468 | ||
| Sequence: |
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| BDBM50261702 | |||
| n/a | |||
| Name | BDBM50261702 | ||
| Synonyms: | 2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)ethoxy}benzyl]-1,3-dioxane-s-2-carboxylic acid | CHEMBL467349 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H27NO6 | ||
| Mol. Mass. | 437.485 | ||
| SMILES | Cc1oc(nc1CCOc1ccc(C[C@H]2CO[C@](C)(OC2)C(O)=O)cc1)-c1ccccc1 |r,wU:17.22,14.14,wD:17.18,(-6.59,-51.43,;-6.28,-49.93,;-7.32,-48.79,;-6.56,-47.45,;-5.05,-47.76,;-4.87,-49.29,;-3.53,-50.05,;-2.2,-49.27,;-.86,-50.03,;.46,-49.25,;1.8,-50.01,;3.13,-49.24,;3.12,-47.69,;4.44,-46.91,;5.78,-47.67,;7.1,-46.88,;8.44,-47.65,;8.45,-49.19,;9.91,-48.74,;7.12,-49.96,;5.79,-49.2,;8.94,-50.65,;10.45,-50.96,;7.92,-51.8,;1.77,-46.93,;.45,-47.72,;-7.2,-46.05,;-6.29,-44.8,;-6.93,-43.4,;-8.47,-43.25,;-9.36,-44.51,;-8.72,-45.91,)| | ||
| Structure | 
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