| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50272415 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_510232 (CHEMBL1005610) |
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| IC50 | >4000±n/a nM |
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| Citation |  Chen, JJ; Qian, W; Biswas, K; Viswanadhan, VN; Askew, BC; Hitchcock, S; Hungate, RW; Arik, L; Johnson, E Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists. Bioorg Med Chem Lett18:4477-81 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40508.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46663 |
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| Residue: | 353 |
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| Sequence: | MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50272415 |
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| n/a |
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| Name | BDBM50272415 |
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| Synonyms: | 2-(1-(mesitylsulfonyl)-3-oxo-1,2,3,4-tetrahydronoxalin-2-yl)-N-(2-methoxyphenyl)acetamide | CHEMBL498679 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N3O5S |
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| Mol. Mass. | 493.575 |
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| SMILES | COc1ccccc1NC(=O)CC1N(c2ccccc2NC1=O)S(=O)(=O)c1c(C)cc(C)cc1C |
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| Structure | 
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