| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
|---|
| Ligand | BDBM50265270 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_496449 (CHEMBL1004580) |
|---|
| IC50 | 500±n/a nM |
|---|
| Citation |  Sundriyal, S; Viswanad, B; Ramarao, P; Chakraborti, AK; Bharatam, PV New PPARgamma ligands based on barbituric acid: virtual screening, synthesis and receptor binding studies. Bioorg Med Chem Lett18:4959-62 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor gamma |
|---|
| Name: | Peroxisome proliferator-activated receptor gamma |
|---|
| Synonyms: | Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 57593.55 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1453700 |
|---|
| Residue: | 505 |
|---|
| Sequence: | MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
|
|
|
|---|
| BDBM50265270 |
|---|
| n/a |
|---|
| Name | BDBM50265270 |
|---|
| Synonyms: | 5-(4-((10H-phenoxazin-10-yl)methyl)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione | CHEMBL496119 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H19N3O5 |
|---|
| Mol. Mass. | 441.4355 |
|---|
| SMILES | O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]\c2ccc(-[#8]-[#6]-[#6]-[#7]-3-c4ccccc4-[#8]-c4ccccc-34)cc2)-[#6](=O)-[#7]-1 |
|---|
| Structure | 
|
|---|
Search and Browse
