| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
|---|
| Ligand | BDBM50219498 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_497170 (CHEMBL1002070) |
|---|
| IC50 | 290000±n/a nM |
|---|
| Citation |  Bayram, E; Senturk, M; Kufrevioglu, OI; Supuran, CT In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. Bioorg Med Chem16:9101-5 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 2 |
|---|
| Name: | Carbonic anhydrase 2 |
|---|
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29250.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00918 |
|---|
| Residue: | 260 |
|---|
| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
|
|
|
|---|
| BDBM50219498 |
|---|
| n/a |
|---|
| Name | BDBM50219498 |
|---|
| Synonyms: | 2-hydroxy-5-sulfo-benzoic acid | 5-Sulfosalicylic acid | CHEMBL229241 | MECLOCYCLINE SULFOSALICYLATE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H6O6S |
|---|
| Mol. Mass. | 218.184 |
|---|
| SMILES | OC(=O)c1cc(ccc1O)S(O)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
