| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50027663 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537445 (CHEMBL990610) |
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| Ki | 0.114000±n/a nM |
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| Citation |  Sabio, M; Jones, K; Topiol, S Use of the X-ray structure of the beta2-adrenergic receptor for drug discovery. Part 2: Identification of active compounds. Bioorg Med Chem Lett18:5391-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50027663 |
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| n/a |
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| Name | BDBM50027663 |
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| Synonyms: | 1-(9H-Carbazol-4-yloxy)-3-isopropylamino-propan-2-ol | 1-(9H-Carbazol-4-yloxy)-3-isopropylamino-propan-2-ol(carazolol) | 1-(9H-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol | CHEMBL324665 | Carazolol | corazolol |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2O2 |
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| Mol. Mass. | 298.3795 |
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| SMILES | CC(C)NCC(O)COc1cccc2[nH]c3ccccc3c12 |
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| Structure | 
|
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