| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 1 |
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| Ligand | BDBM50256705 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_515047 (CHEMBL1034789) |
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| IC50 | 11.1±n/a nM |
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| Citation |  Terui, Y; Chu, YW; Li, JY; Ando, T; Fukunaga, T; Aoki, T; Toda, Y New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). Bioorg Med Chem Lett18:6321-3 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 1 |
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| Name: | Galanin receptor type 1 |
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| Synonyms: | GALR1_RAT | Galanin R1 | Galanin receptor type 1 | Galnr | Galnr1 | Galr1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38883.91 |
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| Organism: | RAT |
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| Description: | Galanin R1 GALR1 RAT::Q62805 |
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| Residue: | 346 |
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| Sequence: | MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARS
KPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLV
SIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDS
NQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASK
KKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPII
YAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV
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| BDBM50256705 |
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| n/a |
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| Name | BDBM50256705 |
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| Synonyms: | (3S,6S,9S,12S)-3-benzyl-6-((2S,3R)-3-hydroxybutan-2-yl)-9,12-diisopropyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone | CHEMBL474038 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H38N4O5 |
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| Mol. Mass. | 474.593 |
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| SMILES | CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@H](C)[C@@H](C)O |r| |
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| Structure | 
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