| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50412556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_560734 (CHEMBL1010869) |
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| IC50 | 200±n/a nM |
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| Citation |  Wang, Y; Busch-Petersen, J; Wang, F; Kiesow, TJ; Graybill, TL; Jin, J; Yang, Z; Foley, JJ; Hunsberger, GE; Schmidt, DB; Sarau, HM; Capper-Spudich, EA; Wu, Z; Fisher, LS; McQueney, MS; Rivero, RA; Widdowson, KL Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists. Bioorg Med Chem Lett19:114-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41020.84 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_560734 |
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| Residue: | 367 |
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| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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| BDBM50412556 |
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| n/a |
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| Name | BDBM50412556 |
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| Synonyms: | CHEMBL481198 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30F3N3O3S |
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| Mol. Mass. | 461.541 |
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| SMILES | C[C@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)S(=O)(=O)C[C@]12CC[C@H](C[C@@H]1O)C2(C)C |r,TLB:27:26:22.23:28| |
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| Structure | 
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