| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
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| Ligand | BDBM24777 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_565115 (CHEMBL965759) |
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| IC50 | 1980±n/a nM |
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| Citation |  Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem17:2276-81 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 2 |
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| Name: | M-phase inducer phosphatase 2 |
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| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 64985.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 580 |
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| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
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| BDBM24777 |
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| n/a |
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| Name | BDBM24777 |
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| Synonyms: | 5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hydroxy-1,4-naphthoquinone, 4 | CHEMBL43612 | Juglone | Juglone (6a) |
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| Type | Small organic molecule |
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| Emp. Form. | C10H6O3 |
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| Mol. Mass. | 174.1528 |
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| SMILES | Oc1cccc2C(=O)C=CC(=O)c12 |c:8| |
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| Structure | 
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