| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 16 |
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| Ligand | BDBM8344 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537068 (CHEMBL986217) |
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| Kd | >40000±n/a nM |
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| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 16 |
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| Name: | Serine/threonine-protein kinase 16 |
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| Synonyms: | MPSK1 | PKL12 | STK16 | STK16_HUMAN | Serine/threonine-protein kinase 16 | TSF1 | Tyrosine-protein kinase STK16 (STK16) |
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| Type: | Protein |
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| Mol. Mass.: | 34659.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 305 |
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| Sequence: | MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDRE
EAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL
TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS
RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQ
KGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQ
HTTQI
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| BDBM8344 |
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| n/a |
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| Name | BDBM8344 |
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| Synonyms: | 6-aryl-pyrazolo[3,4-b]pyridine analogue 8 | CHEMBL408019 | N-[6-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamide | pyrazolo[3,4-b]pyridine analogue 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N4O2 |
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| Mol. Mass. | 294.308 |
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| SMILES | Oc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2n1 |
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| Structure | 
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