| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein kinase FRK |
|---|
| Ligand | BDBM50263295 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_537126 (CHEMBL988960) |
|---|
| Kd | 122±n/a nM |
|---|
| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein kinase FRK |
|---|
| Name: | Tyrosine-protein kinase FRK |
|---|
| Synonyms: | FRK | FRK_HUMAN | FYN-related kinase | Nuclear tyrosine protein kinase RAK | PTK5 | RAK | SRC | Tyrosine Kinase FRK |
|---|
| Type: | Tyrosine-protein kinase |
|---|
| Mol. Mass.: | 58254.41 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P42685 |
|---|
| Residue: | 505 |
|---|
| Sequence: | MSNICQRLWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAED
LSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGA
IGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRR
RIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRL
GSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLED
PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNV
LVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFG
ILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTF
ETLRWKLEDYFETDSSYSDANNFIR
|
|
|
|---|
| BDBM50263295 |
|---|
| n/a |
|---|
| Name | BDBM50263295 |
|---|
| Synonyms: | 6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-[(3-tert-butyl-phenyl)-amide] 4'-cyclopropylmethyl-amide | CHEMBL515466 | N3-(3-tert-butylphenyl)-N4'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H32N2O2 |
|---|
| Mol. Mass. | 440.5766 |
|---|
| SMILES | Cc1ccc(cc1-c1ccc(cc1)C(=O)NCC1CC1)C(=O)Nc1cccc(c1)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
