| Reaction Details |
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 | Report a problem with these data |
| Target | Cycloartenol synthase |
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| Ligand | BDBM50128065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_515551 (CHEMBL1036572) |
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| IC50 | 1750±n/a nM |
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| Citation |  Balliano, G; Dehmlow, H; Oliaro-Bosso, S; Scaldaferri, M; Taramino, S; Viola, F; Caron, G; Aebi, J; Ackermann, J Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents. Bioorg Med Chem Lett19:718-23 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cycloartenol synthase |
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| Name: | Cycloartenol synthase |
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| Synonyms: | CAS1 | CAS1_ARATH | CYC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 86025.20 |
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| Organism: | Arabidopsis thaliana |
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| Description: | ChEMBL_956102 |
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| Residue: | 759 |
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| Sequence: | MWKLKIAEGGSPWLRTTNNHVGRQFWEFDPNLGTPEDLAAVEEARKSFSDNRFVQKHSAD
LLMRLQFSRENLISPVLPQVKIEDTDDVTEEMVETTLKRGLDFYSTIQAHDGHWPGDYGG
PMFLLPGLIITLSITGALNTVLSEQHKQEMRRYLYNHQNEDGGWGLHIEGPSTMFGSVLN
YVTLRLLGEGPNDGDGDMEKGRDWILNHGGATNITSWGKMWLSVLGAFEWSGNNPLPPEI
WLLPYFLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTVLSLRKELFTVPYHEVNWNE
ARNLCAKEDLYYPHPLVQDILWASLHKIVEPVLMRWPGANLREKAIRTAIEHIHYEDENT
RYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIHDFLWLAEDGMKMQGYNGSQLWDTGF
AIQAILATNLVEEYGPVLEKAHSFVKNSQVLEDCPGDLNYWYRHISKGAWPFSTADHGWP
ISDCTAEGLKAALLLSKVPKAIVGEPIDAKRLYEAVNVIISLQNADGGLATYELTRSYPW
LELINPAETFGDIVIDYPYVECTSAAIQALISFRKLYPGHRKKEVDECIEKAVKFIESIQ
AADGSWYGSWAVCFTYGTWFGVKGLVAVGKTLKNSPHVAKACEFLLSKQQPSGGWGESYL
SCQDKVYSNLDGNRSHVVNTAWAMLALIGAGQAEVDRKPLHRAARYLINAQMENGDFPQQ
EIMGVFNRNCMITYAAYRNIFPIWALGEYRCQVLLQQGE
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| BDBM50128065 |
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| n/a |
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| Name | BDBM50128065 |
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| Synonyms: | CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-bromobenzoyl)-3-fluorophenoxy)-N-methylhexan-1-aminium | [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE | {4-[6-(Allyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl}-(4-bromo-phenyl)-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27BrFNO2 |
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| Mol. Mass. | 448.368 |
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| SMILES | CN(CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(F)c1)CC=C |
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| Structure | 
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