| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 2 |
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| Ligand | BDBM50248206 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543044 (CHEMBL1021285) |
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| IC50 | >200000±n/a nM |
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| Citation |  Rho, HS; Baek, HS; Ahn, SM; Yoo, JW; Kim, DH; Kim, HG Studies on depigmenting activities of dihydroxyl benzamide derivatives containing adamantane moiety. Bioorg Med Chem Lett19:1532-3 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 2 |
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| Name: | Polyphenol oxidase 2 |
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| Synonyms: | Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase |
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| Type: | Protein |
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| Mol. Mass.: | 63923.66 |
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| Organism: | Agaricus bisporus (Common mushroom) |
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| Description: | O42713 |
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| Residue: | 556 |
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| Sequence: | MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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| BDBM50248206 |
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| n/a |
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| Name | BDBM50248206 |
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| Synonyms: | CHEMBL516395 | N-Adamantan-1-yl-2,3-dihydroxy-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO3 |
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| Mol. Mass. | 287.3535 |
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| SMILES | Oc1cccc(C(=O)NC23CC4CC(CC(C4)C2)C3)c1O |TLB:12:13:11.10.16:17,THB:14:13:10:16.15.17,14:15:12.13.18:10,12:11:13.18.14:17| |
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| Structure | 
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