| Reaction Details |
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 | Report a problem with these data |
| Target | cGMP-dependent protein kinase |
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| Ligand | BDBM50248496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_566200 (CHEMBL963281) |
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| IC50 | 0.1±n/a nM |
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| Citation |  Scribner, A; Moore, JA; Ouvry, G; Fisher, M; Wyvratt, M; Leavitt, P; Liberator, P; Gurnett, A; Brown, C; Mathew, J; Thompson, D; Schmatz, D; Biftu, T Synthesis and biological activity of anticoccidial agents: 2,3-diarylindoles. Bioorg Med Chem Lett19:1517-21 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| cGMP-dependent protein kinase |
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| Name: | cGMP-dependent protein kinase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 112911.27 |
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| Organism: | Eimeria tenella |
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| Description: | ChEMBL_469577 |
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| Residue: | 1003 |
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| Sequence: | MGACSSKAQHQTRDPEPREQQAAQEQKSTGPSGAPNDAPAPAEAERKMSGSSATAPKGEM
PTASTGTPEQQQQQQQQQQQQQEQQQHPEHQQSEKQQQHGEEQQQERKPSQQQQNEEAAA
PHKHGGERKVQKAIKQQEDTQAEDARLLGHLEKREKTPSDLSLIRDSLSTNLVCSSLNDA
EVEALANAVEFFTFKKGDVVTKQGESGSYFFIVHSGEFEVIVNDKVVNKILTGQAFGEIS
LIHNSARTATIKTLSEDAALWGVQRQVFRETLKQLSSRNFAENRQFLASVKFFEMLTEAQ
KNVITNALVVQSFQPGQAIVKEGEKGDVLYILKSGKALVSIKNKEVRVLQRGEYFGERAL
LYDEPRSATITAEEPTVCVSIGRDLLDRVLGNLQHVLFRNIMLEALQQSKVFASFPTEQL
SRLIGSVVVKDYPENYIILDRENRTRASASALFSAQGVRFFFVLEGEVSVFAYKDKSSSS
SSSSSSSSSSSSAEGEMELHLIDTLKRGQAFGDEYVLSPNKPFAHCVKSNGPTKLALLTA
SALTATLGGQDIDETLDYNNKLAITKKMYIFRYLSEQQTQTLIKAFKTVRYTQGESIIRE
GEIGSRFFIIKLGEVVILKGEKRVRTLGRHDYFGERALLHDERRSATVAANSPEVDLWVV
DKDVFLQIVKGPMLTHLEERIRMQDTKVEFKDLNVVRVVGRGTFGTVKLVQHIPTQMRYA
LKCVSRKSVVALNQQDHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELYD
AIRKLGLLGRYQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKK
MQGRAYTLVGTPHYMAPEVILGKGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFR
DILAGKLIFPHYVTDQDAINLMKRLLCRLPEVRIGCSINGYKDIKEHAFFSDFDWDRLAG
RDLSPPLLPKGEIYAEDAEEGGLDIEEDEGIELEDEYEWDKDF
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| BDBM50248496 |
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| n/a |
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| Name | BDBM50248496 |
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| Synonyms: | 2-(4-(2-(4-fluorophenyl)-3-(pyridin-4-yl)-1H-indol-6-yl)piperidin-1-yl)ethanol | CHEMBL491503 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26FN3O |
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| Mol. Mass. | 415.5025 |
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| SMILES | OCCN1CCC(CC1)c1ccc2c(c([nH]c2c1)-c1ccc(F)cc1)-c1ccncc1 |
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| Structure | 
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