| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50257781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_565967 (CHEMBL960863) |
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| EC50 | 846±n/a nM |
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| Citation |  Owen, DR; Rodriguez-Lens, M; Corless, MD; Gaulier, SM; Horne, VA; Kinloch, RA; Maw, GN; Pearce, DW; Rees, H; Ringer, TJ; Ryckmans, T; Stammen, BL 2,4-Diaminopyridine delta-opioid receptor agonists and their associated hERG pharmacology. Bioorg Med Chem Lett19:1702-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50257781 |
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| n/a |
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| Name | BDBM50257781 |
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| Synonyms: | 2-(3-(3-methoxyphenyl)-3-methylazetidin-1-yl)pyridin-4-amine | CHEMBL492909 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O |
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| Mol. Mass. | 269.3416 |
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| SMILES | COc1cccc(c1)C1(C)CN(C1)c1cc(N)ccn1 |
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| Structure | 
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