| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50133003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_501237 (CHEMBL975272) |
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| Ki | 11±n/a nM |
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| Citation |  Isensee, K; Amon, M; Garlapati, A; Galaparti, A; Ligneau, X; Camelin, JC; Capet, M; Schwartz, JC; Stark, H Fluorinated non-imidazole histamine H3 receptor antagonists. Bioorg Med Chem Lett19:2172-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48691.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. |
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| Residue: | 445 |
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| Sequence: | MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
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| BDBM50133003 |
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| n/a |
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| Name | BDBM50133003 |
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| Synonyms: | 4-(3-(piperidin-1-yl)propoxy)benzonitrile | 4-(3-Piperidin-1-yl-propoxy)-benzonitrile | CHEMBL129257 | UCL-2138 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O |
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| Mol. Mass. | 244.3321 |
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| SMILES | N#Cc1ccc(OCCCN2CCCCC2)cc1 |
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| Structure | 
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