| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50280346 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_217855 (CHEMBL822178) |
|---|
| IC50 | 2±n/a nM |
|---|
| Citation |  Ojima, I; Kato, K; Jameison, FA; Conway, J; Nakahashi, K; Hagiwara, M; Miyamae, T; Radunz, HE New potent enkephalin analogs containing trifluoromethylamino acid residues Bioorg Med Chem Lett2:219-222 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40465.04 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50280346 |
|---|
| n/a |
|---|
| Name | BDBM50280346 |
|---|
| Synonyms: | (S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5,5,5-trifluoro-pentanoic acid {[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-amide | CHEMBL302523 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H39F3N6O6S |
|---|
| Mol. Mass. | 668.727 |
|---|
| SMILES | CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(F)(F)F)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
