| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50280441 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58794 |
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| Ki | 5.1±n/a nM |
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| Citation |  Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG Dopamine receptor binding properties of some 2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols with non-aromatic substituents in the 5-position Bioorg Med Chem Lett2:399-402 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50280441 |
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| n/a |
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| Name | BDBM50280441 |
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| Synonyms: | 8-Chloro-5-cyclopent-1-enyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol | CHEMBL340855 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20ClNO |
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| Mol. Mass. | 277.789 |
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| SMILES | CN1CCc2cc(Cl)c(O)cc2C(C1)C1=CCCC1 |t:16| |
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| Structure | 
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