| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50280300 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196884 |
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| Ki | 6900±n/a nM |
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| Citation |  Matthews, DP; Edwards, ML; Mehdi, S; Koehl, JR; Wolos, JA; McCarthy, JR (E) and (Z)5′-fluoro olefin carbocyclic nucleosides: effect of olefin geometry on inhibition of s-adenosyl-l-homocysteine hydrolase Bioorg Med Chem Lett3:165-168 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | Adenosylhomocysteinase | Ahcy | SAHH_RAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47537.52 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1507790 |
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| Residue: | 432 |
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| Sequence: | MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVET
AVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHF
KDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMP
INGPFKPDHYRY
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| BDBM50280300 |
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| n/a |
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| Name | BDBM50280300 |
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| Synonyms: | (1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth-(E)-ylidene]-cyclopentane-1,2-diol | CHEMBL295620 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12FN5O2 |
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| Mol. Mass. | 265.2437 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1C\C(=C/F)[C@@H](O)[C@H]1O |
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| Structure | 
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