| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin G |
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| Ligand | BDBM50068898 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_45365 |
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| Ki | 1700±n/a nM |
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| Citation |  Angelastro, MR; Bey, P; Mehdi, S; Janusz, MJ; Peet, NP Janus compounds: dual inhibitors of proteinases Bioorg Med Chem Lett3:525-530 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin G |
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| Name: | Cathepsin G |
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| Synonyms: | CATG_HUMAN | CG | CTSG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28860.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469016 |
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| Residue: | 255 |
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| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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| BDBM50068898 |
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| n/a |
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| Name | BDBM50068898 |
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| Synonyms: | BDBM50281588 | CHEMBL147013 | {1-[2-(1-Benzyl-3,3,3-trifluoro-2-oxo-propylcarbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid tert-butyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34F3N3O5 |
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| Mol. Mass. | 513.5498 |
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| SMILES | CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F |
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| Structure | 
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