| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50282006 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_162611 |
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| IC50 | 9000±n/a nM |
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| Citation |  Holmes, DS; Bethell, RC; Hann, MM; Kitchin, J; Starkey, ID; Storer, R The design and synthesis of novel hydroxyproline inhibitors of HIV-1 proteinase Bioorg Med Chem Lett3:1485-1491 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50282006 |
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| n/a |
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| Name | BDBM50282006 |
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| Synonyms: | (1S,4S)-4-[2-Cyclohexyl-1-((S)-3,3-dimethyl-butyrylamino)-ethyl]-4-hydroxy-1-isobutyl-pyrrolidine-2-carboxylic acid tert-butylamide | CHEMBL290349 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H51N3O3 |
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| Mol. Mass. | 465.7121 |
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| SMILES | CC(C)CN1C[C@@](O)(C[C@H]1C(=O)NC(C)(C)C)[C@H](CC1CCCCC1)NC(=O)CC(C)(C)C |
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| Structure | 
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