| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50282063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_208022 (CHEMBL882138) |
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| Ki | 4300±n/a nM |
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| Citation |  Kim, CU; Misco, PF; Luh, BY; Terry, B; Bisacchi, G; Mansuri, MM (2R, 4S, 5S)-1-(tetrahydro-4-hydroxy-5-methoxy-2-furanyl)thymine: a potent selective inhibitor of herpes simplex thymidine kinase Bioorg Med Chem Lett3:1571-1576 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM50282063 |
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| n/a |
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| Name | BDBM50282063 |
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| Synonyms: | 1-[(2R,4S,5S)-4-Hydroxy-5-(3-phenyl-propoxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione | CHEMBL41698 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2O5 |
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| Mol. Mass. | 346.3777 |
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| SMILES | Cc1cn([C@H]2C[C@H](O)[C@@H](OCCCc3ccccc3)O2)c(=O)[nH]c1=O |
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| Structure | 
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